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Contents |
Introduction to the Fifth Edition and Historical Highlights
Jacob V. Aranda and JOHANNES N. VAN DEN ANKER
2. Clinical Pharmacokinetics in Infants and Children
3. Developmental Pharmacodynamics, Receptor Function, and Drug Action in Newborns and Children
4. Drug Absorption, Distribution, Metabolism, Excretion, and Transporters in Newborns and Children
Stephani L. Stancil, Alenka Chapron, AND Susan M. Abdel-Rahman
5. Pharmacogenetics, Pharmacogenomics, and Pharmacoproteomics in Newborns and Children
Brian D. Chapron AND J. Steven Leeder
6. Ethics of Drug Research in Newborns and Children
7. Precision Medicine and Therapeutic Drug Monitoring
Tomoyuki Mizuno, Philip D. Walson, AND Alexander A. Vinks
8. Drug Formulations for Children
SECTION II: Pharmacology in Special Settings and Population: The Newborn
9. Role of Placenta in Drug Metabolism and Drug Transfer
Jamil M. Kazma, JOHANNES N. VAN DEN ANKER, Karel Allegaert, André Dallmann, AND Homa K. Ahmadzia
10. Maternal Medications During Pregnancy and Lactation
11. Principles of Neonatal Pharmacology
Karel Allegaert AND JOHANNES N. VAN DEN ANKER
12. Renal Function and Excretion of Drugs in the Newborn
JOHANNES N. VAN DEN ANKER AND Karel Allegaert
13. Neuroprotective Drugs and Perinatal Brain Injury
Floris Groenendaal, Manon Benders, Linda de Vries, AND Frank van Bel
14. Pharmacologic Agents for Neonatal Hyperbilirubinemia
David K. Stevenson, Ronald J. Wong, AND Sota Iwatani
15. Pharmacologic Treatment of Neonatal Apnea
Girija Natarajan, Jose Maria de Andrade Lopes, AND Jacob V. Aranda
SECTION III: Pharmacology in Special Settings and Population
16. Therapeutic Applications in Pediatric Intensive Care
Ashok P. Sarnaik, Zahraa H. Al-Lawati, Tageldin M. Ahmed, AND Mary W. Lieh-Lai
17. Drug Therapy in the Pediatric Emergency Department
Maryann E. Mazer-Amirshahi AND James M. Chamberlain
Victoria Tutag Lehr, Geoffrey A. Potts, AND Mirjana Lulic-Botica
19. Ophthalmologic Drugs in Infants and Children
SECTION IV: Antimicrobial Pharmacology
20. Penicillins, Cephalosporins, and Other β-Lactams
Roopali Sharma AND Margaret R. Hammerschlag
21. Glycopeptides, Lipoglycopeptides, and Lipopeptides
Roopali Sharma AND Margaret R. Hammerschlag
Karel Allegaert, Anne Smits, AND JOHANNES N. VAN DEN ANKER
23. Macrolides, Clindamycin, and Oxazolidinones
Jennifer Le AND John S. Bradley
25. Sulfonamides, Dihydrofolate Reductase Inhibitors, and Dapsone
Nynke G.L. Jager AND David M. Burger
26. Tetracyclines, Chloramphenicol, and Metronidazole
Basim I. Asmar AND Nahed Abdel-Haq
Elizabeth A. Ashley AND Sir Nicholas J. White
28. Anthelminthics Drugs in Children
29. Antimycobacterial Drugs (Mycobacterium tuberculosis and Atypical Mycobacteria)
Charles A. Peloquin, Wael A. Alghamdi AND Mohammad H. Al-Shaer
Michael J. Smith, William J. Steinbach, Daniel K. Benjamin, Jr., AND Michael Cohen-Wolkowiez
31. Antivirals in Newborns and Children
Claudette L. Poole, David W. Kimberlin, AND Richard J. Whitley
32. Pharmacology of Antiretroviral Drugs in Pregnant and Breastfeeding Women and Their Newborns
Rachel K. Scott, Mark Mirochnick, Brookie M. Best, AND Natella Rakhmanina
Victoria Tutag Lehr AND Mitchel T. Williams
34. Antidepressants and Mood Stabilizers
Ayman Saleh, Gabrielle Sky Cardwell, Robert L. Findling, AND Adelaide S. Robb
35. Stimulants, ADHD Treatments, and Antipsychotics
Ekaterina Stepanova, Bradley Grant, Adelaide S. Robb, AND Robert L. Findling
Sinno H. P. Simons, Gerbrich E. van den Bosch, AND Dick Tibboel
37. Pharmacologic Management of Neonatal Abstinence Syndrome
Elizabeth Yen, Walter K. Kraft, AND Jonathan M. Davis
SECTION VI: Immunopharmacology, Allergy, and Inflammation
39. Nonsteroidal Anti-Inflammatory Drugs
Sylvain Chemtob, John Jeffrey Reese, Anie Lapointe, Mathieu Nadeau-Vallée, AND Victoria Tutag Lehr
Diana Muñoz-Mendoza, Kim Jackson, Sasha A. Alvarado, AND Sami L. Bahna
Hengameh H. Raissy, Elissa Abrams, H. William Kelly, AND Stanley J. Szefler
42. Immunosuppressive and Immunomodulatory Drugs
Burkhard Tönshoff and Britta Höcker
SECTION VII: Pharmacology of Biologic Drugs
43. Microbial Therapeutics: Beyond Probiotics
Desirée Rivera-Nieves AND Josef Neu
Zaid H. Temrikar, Satyendra Suryawanshi, AND Bernd Meibohm
46. Drugs, Lung Development, and Pulmonary Surfactant
Jan Bonhoeffer AND Ulrich Heininger
SECTION VIII: Cardiorenal Drugs
48. Neonatal Cardiovascular Pharmacology
Regan E. Giesinger, A. R. Bischoff, Stephanie M. Boyd, Amy H. Stanford, AND Patrick J. McNamara
49. Antiarrhythmic Drugs: Disorders of Cardiac Rhythm and Pharmacologic Management
Nikola Dragisic, Patrick J. McNamara , Ian H. Law, AND Luis A. Ochoa
Jean-Pierre Guignard AND Silvia Iacobelli
SECTION IX: Gastrointestinal Pharmacology
Suruchi Batra AND Laurie S. Conklin
53. Drugs in Inflammatory Bowel Diseases
Suruchi Batra AND Laurie S. Conklin
SECTION X: Endocrine and Hematologic Pharmacology
Nicolas C. Nicolaides, Tomoshige Kino, AND George P. Chrousos
Eda Cengiz AND William V. Tamborlane
Jorge Mejia-Corletto AND Paul H. Saenger
Aditi Khokhar, Sheila Perez-Colon, Vatcharapan Umpaichitra, Vivian L. Chin, AND Delbert A. Fisher
Sarah E. Kolnik, Kendell R. German, AND Sandra E. Juul
59. Clinical Pharmacology of Antineoplastic Drugs
Stacey L. Berg, Jennifer H. Foster, AND Lisa R. Bomgaars
SECTION XI: Nutritional Pharmacology, Pharmacotoxidromes, Adverse Drug Reactions, and Interactions
Mary Frances Picciano, Michelle K. McGuire, AND Paul M. Coates
Wayne R. Snodgrass AND Susan C. Smolinske
62. Pediatric Poisonings and Antidotes
63. Adverse Drug Reactions in Newborns and Children
Michael Rieder, Abdelbaset Elzagallaai, AND Bruce Carleton
64. Medication Errors in Children
65. Drug Interactions in Newborns and Children
Kelly P. Shaw AND Shannon Manzi
Appendix A1: Neonatal Drug Formulary
Densley Francois, Mirjana Lulic-Botica, Thomas J. Duggan, and Jacob V. Aranda