Medicine

Concurrent Oral Session I: Engineering Nanomedicine

Concurrent Oral Session I: Engineering Nanomedicine

Concurrent Oral Session I: Engineering Nanomedicine

Much work is needed to design more effective tissue engineering
materials for all organs. This could not be more evident by the fact
that the average lifetime of current orthopedic implants is less than
15 years. Frequently, current implants (for example, bone,
vascular, bladder, etc.) fail due to insufficient integration into
juxtaposed tissues. Nanotechnology offers exciting alternatives to
traditional implants since our tissues are composed of constituent
nanostructured components. For example, bone is composed of
nanofibered hydroxyapatite well-dispersed in a mostly collagen
matrix. Thus, it stands to reason that cells are accustomed to
interacting with nanostructured (not conventionally-structured)
surfaces. Moreover, nanostructured materials have unique surface
properties (such as energy, wettability, topography, etc.) that make
them intriguing for applications involving interactions with
proteins and subsequently cells. For these reasons, the objective
of the present study was to design, synthesize, and test (using in
vitro and in vivo analysis) nanostructured materials for various
tissue engineering applications.

read online

Post Comment