EditorApropos “Clinico-genetic characterisation of anencephalitic Dengue virus 4 associated withmulti-organ involvement”

EditorApropos “Clinico-genetic characterisation of anencephalitic Dengue virus 4 associated withmulti-organ involvement”

EditorApropos “Clinico-genetic characterisation of anencephalitic Dengue virus 4 associated withmulti-organ involvement”

The demonstration of eight novel amino acid alterationsin the non-structural genes of dengue virus type 4 (DENV-4)responsible for encephalitis and multi-organ failures in a fatalcases1is commendable. In order to authenticate its neurotropicproperties, it would be desirable to inoculate it in the centralnervous system of monkeys and attempt an in-situ reverse trans-criptase polymerase chain reaction (RT-PCR) on post-mortemtissues.

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